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Does alcohol cause insulin resistance? LinkBack Thread Tools Display Modes
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Old 12-02-2007, 10:10 AM
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Does alcohol cause insulin resistance?

For myself, I've pretty much identified that having some drinks requires at least 50% more insulin overnight. Yes, this is contrary to the usual argument, which states that alcohol causes hypos because your liver stops releasing sugar to process the alcohol in your bloodstream.

I have tried this alcohol test drinking rum/diet coke, zero carbs (yes, I've verified this). No food, yet my sugars rise overnight (note - my sugars don't move for the first few hours). My usual insulin dose has little effect, I have to increase by about 50%.

Looking for others' experiences with this, as it seems to be difficult to find related info. Thanks.
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Old 12-02-2007, 10:17 AM
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I experienced a persistent unexplained rise last night after downing four beers. Typically I drop. Back in the 70's and 80's I was told that people reacted differently. Some would drop and some would rise. I'd be concerned about treating expected highs then going low as all the documentation suggests.
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Old 12-02-2007, 10:19 AM
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Contrary to the common theme on this site, my endo tells me that alcohol raises blood sugar, and preaches constantly that diabetics should not consume more than tiny amounts.
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Old 12-02-2007, 12:39 PM
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I drink Whiskey on the rocks, and it doesn't affect my blood sugar at all. It's just ethanol, water and some flavouring. Nothing there that will increase blood sugar. It's the snacks that do all the damage ....

There is no reason why alcohol should cause insulin resistance. But if it, for whatever reason, it caused an adrenalin response this would cause the liver to spit out glucose. And that would increase the insulin requirement. Maybe you are allergic to alcohol ...
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Old 12-02-2007, 12:41 PM
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As I understand it, and in simple terms without getting into cell receptors, liver function and the rest--your body treats alcohol the same way it would teat some drugs or even a mild poison.

It processes alcohol first. Your body wants to cleanse your system of things it considers potentially harmful. Alcohol is processed even before most simple or complex sugars that come from food. If you drink a lot, your body is busy with it for a longer time. Whatever you eat along with the alcohol gets put on hold and is not processed until after most of the alcohol is finished.

If you had pizza with your beer, the fats will slow down the utilization of the sugars even more. So much for "bar food."

That's why diabetics can even go low while having a drink, and some experts advise having a tiny snack before drinking, to keep you level while the alcohol is being processed.

This has come up before on this forum. I search should bring up some of the excellent and knowledgeable opinions shared.

My opinion, of course. Mich
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Old 12-02-2007, 01:07 PM
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I actually read recently that alcohol may improve insulin sensitivity! Not sure if it's true. I do drink but not excessively.
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Old 12-02-2007, 01:39 PM
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Hi all,

What are we talking about here when we say that "contrary to what most people say, my bs rises when I drink alcohol, and does not drop" What are you all drinking, moonshine perhaps? Because beer contains carbohydrate, wine contains carbohydrate, cider also. Only pure alcoholic drinks like vodka do not. So it is little wounder that most of you are seeing a rise in bs levels when you drink.
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Old 12-02-2007, 01:51 PM
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Quote:
Originally Posted by Geoff View Post
Hi all,

What are we talking about here when we say that "contrary to what most people say, my bs rises when I drink alcohol, and does not drop" What are you all drinking, moonshine perhaps? Because beer contains carbohydrate, wine contains carbohydrate, cider also. Only pure alcoholic drinks like vodka do not. So it is little wounder that most of you are seeing a rise in bs levels when you drink.
Geoff, I think I speak for all that we're not THAT retarded to drink poor choices of alcohol, something like a vodka cooker with sugar then stupidly wonder why our sugar went up!!!

Most diabetics who ingest ANY alcohol knows what it does to them. I posted that I drink rum (0g carb) and diet coke.

I was just hoping to hear new info from people who drink 0g carb alcohol like, whisky was mentioned, or rum like I do and have their sugar go up later.
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Old 12-02-2007, 02:14 PM
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Geoff,

From what I can find, a glass of red wine contains about 100 calories and 5 grams of carb. For people on a weight loss diet, the calories must be counted. The carbs? I personally do not count 5 grams of carb in wine because it is absorbed so much more slowly, almost like consuming fat. 5 grams of carb for me is .45 units of Novolog if I weren't counting the delay. When drinking wine, I do my dinner or snack bolus like I was eating thin crust pizza--a combo with half up front and 1-3 hours for the rest.

Mark,
I also drink rum and diet Coke, and gin and diet tonic. I drink tequila and fresca, my famous "Fresca-rita." I don't drink any of these all by themselves, usually before or with dinner or a snack. My blood sugar rise occurs later because of all of them, especially if I have two.

Most of my friends are social drinkers and I have always joined them, in moderation. I never drink alcohol during the daytime because I am a wimp and I immediately need a nap.

Mich
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Old 12-02-2007, 04:40 PM
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This is an interesting thread and very topical for me....

I feel much better if I just lay off booze, but I'm English so hey, what can I say....
We tend to drink every day then periodically go on the wagon for varying amounts of time ranging from a few days to 2 years once...more often a couple of months at a time... Since diagnosis I have systematically gone off all my favourite tipples, until I am down to Cuban rum or champagne recently.... I was having a decent sized shot before dinner every night for the last few months, I would say 1.5 to 2 ozs and just before the latest wagonride would often have a second drink later in the evening as well...
My bgs were pretty good throughout that time...I did bear it in mind when I was giving my insulin and once in a while I would have to top up my carbs a tiny bit latish on...


Now here's the odd thing, since I stopped drinking my fastings both in the morning and before meals have been quite a bit higher... usual was 4.2 to 4.8 and now it is 5.3 to 6 and even 6.2 a couple of times.

In a conversation with my endo (not really talking about D and alcohol per se) he made the comment " the body sees alcohol as a fat" not sure what he meant by that, but I think we were discussing heart disease risk at the time.

Only thing that occurs to me is that maybe it is my liver that is a big proponent in my D , although I do have diminished insulin production I am still only using a bolus insulin..
Any thoughts?
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Old 12-02-2007, 05:46 PM
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Quote:
Originally Posted by mark_in_toronto View Post
I posted that I drink rum (0g carb) and diet coke.
What type of rum do you drink? Have you tried some other type of alcohol to see if you experience the same effect?
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Old 12-02-2007, 09:40 PM
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Beer is the only drink that raises my BS even Lite beer and that's because of the carbs. I think 4 beers is about 35 - 45carbs, about the same as regular soda. Hard alcohol usually doesn't cause a rise in BS.
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Old 12-02-2007, 09:44 PM
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i need extra insulin when i drink too... in fact my bsl's skyrocket... everyone is different, just do what suits you!

and isn't rum made of sugar cane (molassis) anyway? so it is high in sugar, just carb free (i think that's possible...) i personally find that all alcohol makes my bsl rise, no matter what...
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Old 12-02-2007, 10:02 PM
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Quote:
Originally Posted by blue_eyed_devil View Post
.... and isn't rum made of sugar cane (molassis) anyway? so it is high in sugar, just carb free (i think that's possible...) ....
All that sugar is turned into alcohol and CO2 during fermentation. And sugar left is removed during distillation. The stuff you drink is essentailly flavoured spirit (ethanol and H2O). There is no sugar in it at all.
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Old 12-03-2007, 01:46 AM
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I asked my consultant about this particular effect, because I was mystified as to why my BG would tend to rise after drinking alcohol, despite drinking 0 carb alcohols - I can get monster rises from red wine (and there are virtually 0 carbs in red wine).

The response I got was that either it was insufficient fast-acting with my evening meal, or a rebound from a low in the night - otherwise he did not know.

The effect of alcohol lowering blood glucose overnight is well known, simply because of the number of people with type 1 who come to the attention of the emergency services because they have gone into a hypoglycemic coma.

I have done some research...

first off there is nothing terribly remarkable about ethanol metabolism. It gets converted into acetate and enters the citric acid cycle - ultimately it is metabolised like a fat. one of the intermediaries (acetaldehyde) is toxic and requires energy to convert it into acetate. This might explain why it tends to displace gluconeogeneis/glucose synthesis in the liver.

I have found 2 studies, 1 in humans

Glucose-lactate interrelationships: effect of ethanol

and 1 in rats

Blackwell Synergy - Addiction Biology, Volume 1 Issue 1 Page 71-83, January 1996 (Article Abstract)

the human study showed that lactate blood levels rose - lactate conversion into glucose dropped to 1/3 the normal rate - experimentally they have demonstrated the classic suppression in glucose production which causes alcohol induced hypos, however they also found...

that glucose conversion to lactate had also decreased - meaning that peripheral utilisation of glucose had dropped also.

in the rats that they used a euglycemic clamp - it's an experimental technique for working out how much insulin is needded to maintain normal BG - the more insulin needed the more insulin resistant your subject has become.

they then gave the rats alcohol (I assume a lot of alcohol) - they found that hepatic production of glucose dropped, but also crucially it was also accompanied by a marked decrease in uptake of glucose and glycogen synthesis in skeletal muscle - the rats became markedly insulin resistant.

so the answer to the question, does alcohol make you insulin resistant? Is Yes, BUT...

it also suppresses the production of glucose by the liver.

which possibly explains why the next day after drinking (particularly when I was younger and used to drink alot), that I would wake up high, take my insulin, and then have the mother of all hypos later on.

The insulin fixes the insulin resistance - my muscles start taking up glucose, however my liver is still knackered by the alcohol, and what does insulin do? Yeah that's right it suppresses the conversion of glycogen to glucose.
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