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04-25-2008, 06:24 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Dec 2006 Location: Hastings Melbourne Australia
Posts: 2,686
| | Quote:
Originally Posted by Dimes  I've read that they are working on a way to develop stem cells from skin cells. Then if they can create islet cells from the stem cells, and figure out the encapsulating technology, it would seem very hopeful for a non-insulin dependent treatment, maybe in the not too-distant future. | Yes that would be good as the islet cells is the carryier of insulin.
Quote: |
Another approach would be figuring out why the auto-immune attack is happening in the first place, and figuring out how to stop it.
| And this is where the lab run by Dr. Denise L. Faustman has this to halt the killer T-cells from attaking the islet cell. 
Thanks everyone. 
__________________ We inject to stay alive!!! So that i can enjoy what you enjoy!!!  A1C for July '08 5.9 MMOL/L
Peter... Insulins Novorapid and Levemir.
So I am well armed to enjoy food of any kind!!!  |
04-25-2008, 06:34 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2006 Location: Auckland, New Zealand
Posts: 1,938
| | | Bob Elliot and his team at Living Cell Technologies have been working on this for a long time. Getting the approval he needs has been a major challenge. The initial tests on implanting encapsulated pig beta cells were stopped by the New Zealand government 10 years ago because of concerns about the risk of xenotransplantation. Recent trials in Russia were very encouraging, and they are waiting for final approval to start the next phase of trials in New Zealand. The government, as usual, is dragging its heels on this. Probably nothing will happen soon as it is an election year. And it seems the trials may be moved to the US. It looks like progress is being made. But it is just so slow! ...
__________________
In my humble opinion  
Type1 since 1977
MDI using Lantus, Protophane, Novorapid and Actrapid
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04-25-2008, 06:42 PM
|  | Senior Member
I am a: Type 2 | | Join Date: Mar 2008 Location: Nova Scotia, Canada
Posts: 1,724
| | Quote:
Originally Posted by Dimes ...if they can create islet cells from the stem cells, and figure out the encapsulating technology, it would seem very hopeful for a non-insulin dependent treatment... | As I understand it: stem cells come from the patient themselves so there would be no risk of rejection... no need for anti-rejection drugs or encapsulation. Now if only someone could convince GWB that the World wasn't created 4,800 years ago (on a Monday morning at 9am) they might actually get on with some stem cell research in the USA 
__________________ ~ Frank Metabolic Syndrome Dx'd March 2003. Started MM 712 Pump April 2004. MM 722 + Contour Link April 2008. "...type 2 diabetes is associated with obesity... [so] most people assume that the excess weight causes the diabetes. But... it's possible that diabetes causes obesity" "One of the causes of your diabetes is a poor choice of ancestors." - Gretchen Becker - The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed |
04-25-2008, 07:20 PM
| | Junior Member
I am a: Type 1 | | Join Date: Feb 2008 Location: Toronto, ON, Canada
Posts: 50
| | Quote:
Originally Posted by fgummett As I understand it: stem cells come from the patient themselves so there would be no risk of rejection... no need for anti-rejection drugs or encapsulation. Now if only someone could convince GWB that the World wasn't created 4,800 years ago (on a Monday morning at 9am) they might actually get on with some stem cell research in the USA | But they still need to protect against the autoimmune attack.. presumably that factor doesn't go away, and is the reason why a lot of "successful' treatments reverse in a year or two.
__________________
Chris
Dx'ed Nov/2007
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04-25-2008, 07:22 PM
| | Senior Member
I am a: Type 2 | | Join Date: Mar 2008 Location: Nova Scotia, Canada
Posts: 1,724
| | Ah..! I didn't realise that the factor was still around. Thanks 
__________________ ~ Frank Metabolic Syndrome Dx'd March 2003. Started MM 712 Pump April 2004. MM 722 + Contour Link April 2008. "...type 2 diabetes is associated with obesity... [so] most people assume that the excess weight causes the diabetes. But... it's possible that diabetes causes obesity" "One of the causes of your diabetes is a poor choice of ancestors." - Gretchen Becker - The First Year: Type 2 Diabetes: An Essential Guide for the Newly Diagnosed |
04-26-2008, 06:19 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Aug 2007 Location: UK
Posts: 509
| | Quote:
Originally Posted by Dimes But they still need to protect against the autoimmune attack.. presumably that factor doesn't go away, and is the reason why a lot of "successful' treatments reverse in a year or two. | Yep and I definitely prefer encapsulation to drugs that suppress the immune system, it is a much better solution. All of this seems achievable with the breakthroughs already made; I really hope they can get the funding and support they need. Only time will tell. |
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