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View Poll Results: How many insulin units per KG of body weight do you use every day? | |
< 0.25 units/Kg
|   | 5 | 10.00% | |
0.26 - 0.50 units/Kg
|   | 21 | 42.00% | |
0.51 - 0.75 units/Kg
|   | 12 | 24.00% | |
0.76 - 1.00 units/Kg
|   | 3 | 6.00% | |
1.01 - 1.25 units/Kg
|   | 2 | 4.00% | |
1.26 - 1.50 units/Kg
|   | 3 | 6.00% | |
> 1.50 units/Kg
|   | 4 | 8.00% |  | | 
04-22-2008, 03:26 AM
|  | Member
I am a: Type 1 | | Join Date: Aug 2006 Location: NJ
Posts: 483
| | | .55 or so.
Weight is 66kg
I am pumping about 36 units a day on average.
I consume about 175 to 200 carbs/day
__________________
Type 1 since 4/74
Pump user since 10/17/06!
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04-22-2008, 03:59 AM
| | Senior Member
I am a: Type 1 | | Join Date: Jan 2007 Location: UK, Hampshire
Posts: 524
| | | I'm on .56u per Kg
that's with a daily carb intake around the 250g mark. | 
04-22-2008, 11:46 AM
| | Member
I am a: Type 1 | | Join Date: Aug 2006 Location: Chepstow, Wales, UK
Posts: 148
| | | 31.5 units/80kg=.39 on av
eating 150grms carb/day avg
__________________
Diagnosed June 10 2005. Type 1
A1C Feb 6.3 2008
A1C Nov 6.1
A1C Aug 6.1
A1C May 6.0
A1C Mar 6.0 2007
A1C Dec 6.3
A1C Sep 6.0
A1C Jun 6.1 2006
Changed from Lantus to Levemir split dose 4 units night/13units morning
NovaRapid 3x/day,0.5unit, 2-3.5units, 3-4.5units
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04-22-2008, 12:32 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 509
| | | 84 kg (maybe a little less now)
300 +/- 20% grams of CHO per day (1:15 I:C ratio)
33 U basal
Typically low-50s U/day leaves me around 0.65 U/kg TDD.
__________________
Eddy
DXed 2007/04 : presented with advanced-stage DKA, A1c of 12.9%, and BMI of 21.3 kg/m^2
Post-DX A1c : 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
current BMI : 25.4 (84kg on 182cm); want to get back to 23-24
basal : Levemir; 18U @ 0800, 18U @ 2200 (have also used Lantus)
bolus : 1:15 I:C ratio; varying mix of Novolog, Novolin-R, Novolin-N (have also used Humalog, Humulin-R, and Humulin-N)
not a low-CHO eater... not even close!
last updated 2008/05/09 | 
04-22-2008, 12:33 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Jan 2008 Location: Kansas, US
Posts: 509
| | Quote:
Originally Posted by BlueSky I am interested in seeing what the spread for Type 1 members is. | I'd like to see TDD/mass correlated with c-peptide levels and I:C ratios.
__________________
Eddy
DXed 2007/04 : presented with advanced-stage DKA, A1c of 12.9%, and BMI of 21.3 kg/m^2
Post-DX A1c : 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
current BMI : 25.4 (84kg on 182cm); want to get back to 23-24
basal : Levemir; 18U @ 0800, 18U @ 2200 (have also used Lantus)
bolus : 1:15 I:C ratio; varying mix of Novolog, Novolin-R, Novolin-N (have also used Humalog, Humulin-R, and Humulin-N)
not a low-CHO eater... not even close!
last updated 2008/05/09 | 
04-22-2008, 03:57 PM
|  | Member
I am a: Type 1 | | Join Date: Jul 2004 Location: Livonia, MI
Posts: 447
| | | 200 pounds = 91kg. Latest 31 day avg. = 59 units.
59/91=0.65units/kg.
32 units is basal, leaving about 27 units for CHO/Correction...
__________________ <scott>
<T1 for 20 years - Clear Paradigm 722 w/ CGMS>
<4.23.08 A1C --> 6.2>
<1.23.08 A1C --> 6.5> | 
04-22-2008, 03:59 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2006 Location: Auckland, New Zealand
Posts: 1,601
| | That poll has been an interesting exercise. Finding a "normal" insulin sensitivity reference point was not easy. The best I could find is John Walsh's suggestion that weight in pounds divided by 4 approximates the insulin need for someone with normal insulin sensitivity. Quote:
For those with Type I diabetes, insulin sensitivity can be estimated by filling in the blanks below:
1. Your weight (lbs.) / 4 =_____ units
2. Your total daily insulin dose (all insulins) =_____ units
The answer from line 1, (weight divided by 4) gives your estimated need for insulin. If your actual insulin dose on line 2 is close to this number, and you have good control, you have a normal sensitivity to insulin.
If line 2 is less than line 1 (and your control is good), you have excellent insulin sensitivity.
If line 2 is much greater than line 1, your insulin sensitivity may be lower or you may be on too much insulin. Insulin Sensitivity | This equates to 0.55 units/Kg for a person weighing 150 lbs. As a group, we appear to have pretty normal insulin sensitivity, according to this definition of normal.
Thanks for your responses 
__________________
In my humble opinion
Type1 since 1977
MDI using Lantus, Protophane, Novorapid and Actrapid
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04-22-2008, 04:00 PM
|  | Member
I am a: Type 1 | | Join Date: Nov 2007 Location: Mid-Missouri
Posts: 154
| | | About 73kg
250-350 CHO/day
31 units TDD based on 30 day average
So somewhere around .43 u/kg
__________________
When the power of love overcomes the love of power, the world will know peace.
-Jimi Hendrix
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04-22-2008, 04:18 PM
| | Member
I am a: Type 1 | | Join Date: Aug 2007 Location: UK
Posts: 355
| | | 1. Your weight (141 lbs.) / 4 = 35.25 units
2. Your total daily insulin dose (all insulins) = 18 units
Surely Insulin resistance/sensitivity isn’t the only factor, beta cell productivity comes into play as well. It’s an interesting formula I wonder if once my beta cells finally give up the ghost my TDD will go up to the expected 35units or close to.
__________________
A1c 6.1 - 29th of Novemember 2007
A1c 8.1 - 23rd of May 2007
Diagnosed 27th of August 2006
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04-22-2008, 04:32 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2006 Location: Auckland, New Zealand
Posts: 1,601
| | This calculation only applies to people with no residual beta cell function. There are other noise factors too, like level of carbohydrate consumption, insulin delivery method, age, hormonal activity etc. This is why there is variation around the norm. When your beta cells finally pack up, yes, you can expect to see an increase in exogenous insulin requirements towards this benchmark. But if you stay in shape and get lots of exercise, you should continue to be relatively insulin sensitive. My number works out to 0.47 units/Kg, but I have been T1 for 30 years and my beta cells are completely dead .... 
__________________
In my humble opinion
Type1 since 1977
MDI using Lantus, Protophane, Novorapid and Actrapid
| 
04-22-2008, 07:29 PM
| | Senior Member
I am a: Type 1 | | Join Date: Sep 2004
Posts: 5,131
| | | 0.31 for me.
blah blah blah
__________________
Officially type 1, really type "we-have-no-stinkin'-clue"
Clear Minimed Paradigm 522 w/ occasional sensor use
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04-23-2008, 02:48 AM
| | Member
I am a: Type 1.5 | | Join Date: Jan 2005 Location: South Africa
Posts: 173
| | | TDD: 18u, 73Kg, 0.25/Kg
Lowish carb eating plan
My beta cells still do a bit. . . . | 
04-23-2008, 11:16 AM
|  | Member
I am a: Type 1 | | Join Date: Jul 2007 Location: Canada, Prince Edward Island
Posts: 368
| | | So for me it looks like my 170lbs = 77kg
On Average 18 Units a day.
SO
I am at less then .25
More of a 0.23 if I did that right.
My Beta Cells are still doing some work for me. | 
04-23-2008, 11:51 AM
|  | Senior Member
I am a: Type 1 | | Join Date: Oct 2006
Posts: 802
| | Quote:
Originally Posted by BlueSky That poll has been an interesting exercise. Finding a "normal" insulin sensitivity reference point was not easy. The best I could find is John Walsh's suggestion that weight in pounds divided by 4 approximates the insulin need for someone with normal insulin sensitivity.
This equates to 0.55 units/Kg for a person weighing 150 lbs. As a group, we appear to have pretty normal insulin sensitivity, according to this definition of normal.
Thanks for your responses  | This is interesting.
I found the following reference in a book partially captured by Google Books -- Type 1 Diabetes in Children ... - Google Book Search
If I read that page correctly, it looks like that book says that for adults without diabetes, normal native I guess insulin production is on the level of .5 u/kg per day. But for adult diabetics, the sensitivity factor is more like .7 - .8 u/kg per day. | 
04-23-2008, 12:55 PM
|  | Senior Member
I am a: Type 1 | | Join Date: Sep 2006 Location: Auckland, New Zealand
Posts: 1,601
| | Quote:
Originally Posted by Scratch .... Type 1 Diabetes in Children ... - Google Book Search
If I read that page correctly, it looks like that book says that for adults without diabetes, normal native I guess insulin production is on the level of .5 u/kg per day. But for adult diabetics, the sensitivity factor is more like .7 - .8 u/kg per day. | That looks like a very a useful book. But I wonder why they distinguish between the insulin needs of normal adults and adults with type 1 diabetes. I can see no logical reason for an adult T1 to be more insulin resistant than a normal adult. 
__________________
In my humble opinion
Type1 since 1977
MDI using Lantus, Protophane, Novorapid and Actrapid
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