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View Poll Results: How many insulin units per KG of body weight do you use every day?
< 0.25 units/Kg 5 10.00%
0.26 - 0.50 units/Kg 21 42.00%
0.51 - 0.75 units/Kg 12 24.00%
0.76 - 1.00 units/Kg 3 6.00%
1.01 - 1.25 units/Kg 2 4.00%
1.26 - 1.50 units/Kg 3 6.00%
> 1.50 units/Kg 4 8.00%
Voters: 50. You may not vote on this poll

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  #16 (permalink)  
Old 04-22-2008, 03:26 AM
Gordonm's Avatar
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I am a: Type 1
 
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.55 or so.
Weight is 66kg
I am pumping about 36 units a day on average.
I consume about 175 to 200 carbs/day
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  #17 (permalink)  
Old 04-22-2008, 03:59 AM
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Location: UK, Hampshire
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I'm on .56u per Kg

that's with a daily carb intake around the 250g mark.
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  #18 (permalink)  
Old 04-22-2008, 11:46 AM
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I am a: Type 1
 
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Location: Chepstow, Wales, UK
Posts: 148
31.5 units/80kg=.39 on av
eating 150grms carb/day avg
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  #19 (permalink)  
Old 04-22-2008, 12:32 PM
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84 kg (maybe a little less now)
300 +/- 20% grams of CHO per day (1:15 I:C ratio)
33 U basal

Typically low-50s U/day leaves me around 0.65 U/kg TDD.
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DXed 2007/04 : presented with advanced-stage DKA, A1c of 12.9%, and BMI of 21.3 kg/m^2
Post-DX A1c : 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
current BMI : 25.4 (84kg on 182cm); want to get back to 23-24
basal : Levemir; 18U @ 0800, 18U @ 2200 (have also used Lantus)
bolus : 1:15 I:C ratio; varying mix of Novolog, Novolin-R, Novolin-N (have also used Humalog, Humulin-R, and Humulin-N)
not a low-CHO eater... not even close!
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  #20 (permalink)  
Old 04-22-2008, 12:33 PM
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Quote:
Originally Posted by BlueSky View Post
I am interested in seeing what the spread for Type 1 members is.
I'd like to see TDD/mass correlated with c-peptide levels and I:C ratios.
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Eddy


DXed 2007/04 : presented with advanced-stage DKA, A1c of 12.9%, and BMI of 21.3 kg/m^2
Post-DX A1c : 5.2% @ 2008/04; 5.3% @ 2007/12; 5.3% @ 2007/08
current BMI : 25.4 (84kg on 182cm); want to get back to 23-24
basal : Levemir; 18U @ 0800, 18U @ 2200 (have also used Lantus)
bolus : 1:15 I:C ratio; varying mix of Novolog, Novolin-R, Novolin-N (have also used Humalog, Humulin-R, and Humulin-N)
not a low-CHO eater... not even close!
last updated 2008/05/09
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  #21 (permalink)  
Old 04-22-2008, 03:57 PM
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I am a: Type 1
 
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200 pounds = 91kg. Latest 31 day avg. = 59 units.

59/91=0.65units/kg.

32 units is basal, leaving about 27 units for CHO/Correction...
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  #22 (permalink)  
Old 04-22-2008, 03:59 PM
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That poll has been an interesting exercise. Finding a "normal" insulin sensitivity reference point was not easy. The best I could find is John Walsh's suggestion that weight in pounds divided by 4 approximates the insulin need for someone with normal insulin sensitivity.
Quote:
For those with Type I diabetes, insulin sensitivity can be estimated by filling in the blanks below:

1. Your weight (lbs.) / 4 =_____ units
2. Your total daily insulin dose (all insulins) =_____ units

The answer from line 1, (weight divided by 4) gives your estimated need for insulin. If your actual insulin dose on line 2 is close to this number, and you have good control, you have a normal sensitivity to insulin.

If line 2 is less than line 1 (and your control is good), you have excellent insulin sensitivity.

If line 2 is much greater than line 1, your insulin sensitivity may be lower or you may be on too much insulin.
Insulin Sensitivity
This equates to 0.55 units/Kg for a person weighing 150 lbs. As a group, we appear to have pretty normal insulin sensitivity, according to this definition of normal.

Thanks for your responses
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  #23 (permalink)  
Old 04-22-2008, 04:00 PM
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Location: Mid-Missouri
Posts: 154
About 73kg
250-350 CHO/day
31 units TDD based on 30 day average
So somewhere around .43 u/kg
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  #24 (permalink)  
Old 04-22-2008, 04:18 PM
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Posts: 355
1. Your weight (141 lbs.) / 4 = 35.25 units
2. Your total daily insulin dose (all insulins) = 18 units

Surely Insulin resistance/sensitivity isn’t the only factor, beta cell productivity comes into play as well. It’s an interesting formula I wonder if once my beta cells finally give up the ghost my TDD will go up to the expected 35units or close to.
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  #25 (permalink)  
Old 04-22-2008, 04:32 PM
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This calculation only applies to people with no residual beta cell function. There are other noise factors too, like level of carbohydrate consumption, insulin delivery method, age, hormonal activity etc. This is why there is variation around the norm. When your beta cells finally pack up, yes, you can expect to see an increase in exogenous insulin requirements towards this benchmark. But if you stay in shape and get lots of exercise, you should continue to be relatively insulin sensitive. My number works out to 0.47 units/Kg, but I have been T1 for 30 years and my beta cells are completely dead ....
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  #26 (permalink)  
Old 04-22-2008, 07:29 PM
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0.31 for me.

blah blah blah
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  #27 (permalink)  
Old 04-23-2008, 02:48 AM
dbc dbc is offline
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I am a: Type 1.5
 
Join Date: Jan 2005
Location: South Africa
Posts: 173
TDD: 18u, 73Kg, 0.25/Kg
Lowish carb eating plan
My beta cells still do a bit. . . .
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  #28 (permalink)  
Old 04-23-2008, 11:16 AM
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So for me it looks like my 170lbs = 77kg
On Average 18 Units a day.
SO
I am at less then .25
More of a 0.23 if I did that right.

My Beta Cells are still doing some work for me.
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  #29 (permalink)  
Old 04-23-2008, 11:51 AM
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Quote:
Originally Posted by BlueSky View Post
That poll has been an interesting exercise. Finding a "normal" insulin sensitivity reference point was not easy. The best I could find is John Walsh's suggestion that weight in pounds divided by 4 approximates the insulin need for someone with normal insulin sensitivity.


This equates to 0.55 units/Kg for a person weighing 150 lbs. As a group, we appear to have pretty normal insulin sensitivity, according to this definition of normal.

Thanks for your responses
This is interesting.

I found the following reference in a book partially captured by Google Books --

Type 1 Diabetes in Children ... - Google Book Search

If I read that page correctly, it looks like that book says that for adults without diabetes, normal native I guess insulin production is on the level of .5 u/kg per day. But for adult diabetics, the sensitivity factor is more like .7 - .8 u/kg per day.
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  #30 (permalink)  
Old 04-23-2008, 12:55 PM
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Quote:
Originally Posted by Scratch View Post
.... Type 1 Diabetes in Children ... - Google Book Search

If I read that page correctly, it looks like that book says that for adults without diabetes, normal native I guess insulin production is on the level of .5 u/kg per day. But for adult diabetics, the sensitivity factor is more like .7 - .8 u/kg per day.
That looks like a very a useful book. But I wonder why they distinguish between the insulin needs of normal adults and adults with type 1 diabetes. I can see no logical reason for an adult T1 to be more insulin resistant than a normal adult.
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