[kid_fears99]

So, for any of you who have read my other post, I've been having DP for about a month. Then, "randomly" (or so I thought), I woke up Saturday morning in a normal range. Again on Monday, I woke up normal. I started pondering the connection, and came to this - both nights before going to bed I took Ibuprofen (I broke my toe Friday and I am taking it for pain). Basically, all other things were equal (i.e. time I went to bed, woke up, generally what I ate the night before in terms of fat content and carbs, BGLs before I went to bed, etc.) So I'm thinking, maybe my liver spends its time dealing with the Ibuprofen instead of pumping glycogen into my body? Last night, I purposefully did not take Ibuprofen before bed to test my theory out and sure enough, I woke up at 345. Just wondering what you guys think about my theory?

[seacomp]

Originally Posted by kid_fears99

Just wondering what you guys think about my theory?

Please test some more.

[Simon]

You might like to read:

http://www.daref.org/z4040.html

[DeusXM]

Keeping your liver occupied overnight is a great way to stave off DP.

A safer way than regularly taking ibuprofen is to have a small alcoholic drink before going to bed - like a glass of red wine or whiskey.

Seriously, next time your local paper runs an article on someone seeing their hundredth birthday, £10 says that the birthday boy or girl will say they have a glass of whiskey every night.

[Angelique]

Seriously, next time your local paper runs an article on someone seeing their hundredth birthday, £10 says that the birthday boy or girl will say they have a glass of whiskey every night.

That's to funny. I have never heard of that before.



That is very interesting about the ibuprofen. It's amazing what affects our bg's.


I stopped eating after 7:00pm to avoid major issues with highs when at 3:00am and that is the time my basal rate on my pump has the highest amount.

[JasonSmithMT]

Ibuprofen doesn't really "occupies the liver" in the same way alcohol does so my thought on your theory is that it is not really having anything to do with the liver. Alcohol can indeed suppress the liver's natural release of glucose (gluconeogenesis) by disrupting the NADH-to-NAD ratio. Nothing that I am aware of with ibuprofen's pharmacologic action does it get involved in anything that would disrupt gluconeogenesis. Ibuprofen mechanism of elimination is mainly the kidneys. A good amount of diabetics who take ibuprofen will in fact see a slight increases in glucose levels.

Do you have any 2am or 3am glucose levels on those days? The reason I ask is that my first thought was that your early morning highs could be because of rebound hyperglycemia due to hypoglycemia during the night and that the ibuprofen could have kept your glucose level high enough to not cause hypoglycemia.

Jason

[Aftiel]

Ibuprofen may be helping due to the fact that is helps relax the body (muscles.)

More relaxed = less stress = lower BG.

Alcohol would have the same effect I would think.

- Aftiel

[Doetsch]

When I was succeptable to DP more when I was younger. My doctor told my parents that a way to fix it is to have a little alcohol at bedtime. I was 17 at the time and my parents felt that I was old enough to have a little alcohol so my dad would give me a small amount of Rum and Diet Coke every night. This fixed the problem and my friends always hated it saying "Man I wish I was Diabetic so my parents would give me Liquor".