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Metformin vs Metformin XR LinkBack Thread Tools Display Modes
  #1 (permalink)  
Old 03-06-2007, 06:30 PM
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Metformin vs Metformin XR

Hi, I'm sorry, another question! I guess I'm needy tonite..

I'm wondering about the advantages and disadvantages of of the extended release form of Metformin?
Do you only have to take the pill once a day??

I"m having an issue remembering to take mine twice a day and in a timely manner... If I could take it just once a day, that would be so much better for me....

Suggestions would be helpful... thanks! again..!!!
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  #2 (permalink)  
Old 03-06-2007, 07:15 PM
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I tried both. Reg Metformin gave me headaches 24/7 and I am not prone to headaches normally. Too much blood glucose fluctuation was at the root of my problem with reg Metformin.

I am now on extended release. I like it a lot! I take 500mg with breakfast and 500mg with supper. Works well for me.

I too would forget... Or I thought I had forgotten and then took too much. Ack!

I got a dosette and now I don't forget my meds nor my vitamins. That dosette is quite useful as I don't even have to take the whole thing with me let's say I'm out for the day or gone for a week-end. I just take with me the days I'll need and leave the rest home. Handy!
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  #3 (permalink)  
Old 03-06-2007, 07:46 PM
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Thanks Marie... altho that wasn't what I was hoping for... so... I guess .... the next question is...

Is there any oral medication for type 2's that you only take once a day?? Something that gives 24hr coverage??

Traci
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  #4 (permalink)  
Old 03-06-2007, 08:19 PM
ladytaz's Avatar
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alot of people only take the XR only once a day Traci. Ask your doc about it
__________________
Age: 43
Type 2 - Dx'd 08.16.05
•••
[ A1c ]
6.9 - 01/07
6.0 - 05/07
5.9 - 09/07
6.4 - 3/08
[ Meter ]
UltraSmart/Ultra2/Contour
[ Meds ]
Metformin 1000mg 2x, Novolin N 20u 2x, Novolin R 1:10
Lisinopril 20mg 1x, Lovastatin 40mg 1x, Aspirin 81mg 1x, Albuterol as needed
[ Other Conditions ]
Coccidioidomycosis aka Valley Fever Dx'd 1.17.94
- Asthma
- Chronic Bronchitis
Hypertention
Hyperlipidemia


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  #5 (permalink)  
Old 03-07-2007, 02:23 AM
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I was on regular Metformin and switched to the XR version after having stomach probs. I used to take 4 x 500mg daily, 2 in the morning and 2 in the evening, since the switch I now take 2 x 500mg XR both in the evening. I have also had to suppliment this with 80mg of gliclazide as my numbers were getting a lil out of control, but that is taken in the morning.

I suppose it depends what kind of medication you take but like ladytaz says many folks on XR only take it once a day.

As we have all discoverd there is no such thing as a standard diabetic, what works for one will send another crazy low or stupid high.

When i first started out I used to take metformin morn, lunch and eve, I was always forgetting the lunch one and it was a pain because if you left the house you had to take your meds with you.

I would welcome a once a day treatment, these are available as a combination of metformin type meds and gliclazide type meds. but most of the people I have heard of taking them were switched from them maximum doses of metformin and gliclazide combined
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  #6 (permalink)  
Old 03-07-2007, 06:39 AM
orpy's Avatar
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Metformin extended

Hi,

I'm just starting a regimen of Metformin XR and I take it at night (the whole dose). Anyway, I'm very concerned with the morning BG readings I'm getting since I started Metformin. The endo nurse practioner put me on it to lower my morning readings. So far they've been sky-high (numbers I've never had before); much higher than what she deemed too high before taking the metformin.

This morning at 6:00 am it was 162...other days it's been higher. She doubled the dose from 500mg and said to call in two weeks. I'm kind of freaking out because I take my BG very seriously. This morning my right eye was blurry, something I haven't experienced since prior to my diagnosis.

My question is, is it worth it to experiment and have high BG while we're figuring out the meds? Also, has anyone experienced high BG readings on taking Metformin. I work hard to keep my numbers down and frankly, it's really bothering me getting these morning readings. But if it's a matter of the Metformin kicking in after two weeks, then I guess I can wait for that...I just worry about the cumulative damage done while we futz around with meds.
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A1C changes: 6.8-->6.6-->6.5-->6.1-->6.4-->7.2 --> 6.0-->6.4 (11/2008)

Type 2 or 1.5?

Lantus
Humalog

I have my ups and downs.
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  #7 (permalink)  
Old 03-07-2007, 11:42 AM
ladytaz's Avatar
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Quote:
Originally Posted by orpy View Post
Hi,

I'm just starting a regimen of Metformin XR and I take it at night (the whole dose). Anyway, I'm very concerned with the morning BG readings I'm getting since I started Metformin. The endo nurse practioner put me on it to lower my morning readings. So far they've been sky-high (numbers I've never had before); much higher than what she deemed too high before taking the metformin.

This morning at 6:00 am it was 162...other days it's been higher. She doubled the dose from 500mg and said to call in two weeks. I'm kind of freaking out because I take my BG very seriously. This morning my right eye was blurry, something I haven't experienced since prior to my diagnosis.

My question is, is it worth it to experiment and have high BG while we're figuring out the meds? Also, has anyone experienced high BG readings on taking Metformin. I work hard to keep my numbers down and frankly, it's really bothering me getting these morning readings. But if it's a matter of the Metformin kicking in after two weeks, then I guess I can wait for that...I just worry about the cumulative damage done while we futz around with meds.
Orpy, were you taking the "regular" metformin before? Or is this your first experience taking metformin all together?

If you've not taken it before, I don't see why it would RAISE your BLG's .... but the blurry vision and such is often a side effect, while your body gets used to better BGL's. It's often quite normal to go up and down with the BGL as well, it's almost like the high and low are fighting

If you HAVE been taking Metformin, and they've just switched you from "regular" to XR, then you shouldn't see any changes I wouldn't think, at least any changes should be for the BETTER, not worse!! (usually having to do with side effects going away, and having more steady BGL). You MAY need to start on something like Glipizide in addition to the Metformin, if this is the case. Your body may not be producing enough insulin, which is what Glipizide will make it do. The Metformin, helps your body to properly use the insulin your body makes.

But no, I really can't see your morning nubmers rising JUST from the metformin! That doesn't make sense, then again, what in Diabetes makes sense?

Keep on top of it, and keep on top of your Doctor and/or Nurse Practitioner about it tho!!
__________________
Age: 43
Type 2 - Dx'd 08.16.05
•••
[ A1c ]
6.9 - 01/07
6.0 - 05/07
5.9 - 09/07
6.4 - 3/08
[ Meter ]
UltraSmart/Ultra2/Contour
[ Meds ]
Metformin 1000mg 2x, Novolin N 20u 2x, Novolin R 1:10
Lisinopril 20mg 1x, Lovastatin 40mg 1x, Aspirin 81mg 1x, Albuterol as needed
[ Other Conditions ]
Coccidioidomycosis aka Valley Fever Dx'd 1.17.94
- Asthma
- Chronic Bronchitis
Hypertention
Hyperlipidemia


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  #8 (permalink)  
Old 03-07-2007, 11:46 AM
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Quote:
Originally Posted by ladytaz View Post
Orpy, were you taking the "regular" metformin before? Or is this your first experience taking metformin all together?

But no, I really can't see your morning nubmers rising JUST from the metformin! That doesn't make sense, then again, what in Diabetes makes sense?
No, I wasn't on it before...this is a new drug. My blood sugar readings in the a.m. are higher than they were before...

She did say that once in a great while she sees someone who's blood sugar goes up with Metformin...

I just hate wasting time trying to get a correct med...sometimes I feel like I did better without all the meds.
__________________
Orpy

A1C changes: 6.8-->6.6-->6.5-->6.1-->6.4-->7.2 --> 6.0-->6.4 (11/2008)

Type 2 or 1.5?

Lantus
Humalog

I have my ups and downs.
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  #9 (permalink)  
Old 03-07-2007, 11:56 AM
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Quote:
Originally Posted by orpy View Post
No, I wasn't on it before...this is a new drug. My blood sugar readings in the a.m. are higher than they were before...

She did say that once in a great while she sees someone who's blood sugar goes up with Metformin...

I just hate wasting time trying to get a correct med...sometimes I feel like I did better without all the meds.
hmmm well that IS very weird indeed! Again, you may need something like Glipizide to go with it? They do need a good three weeks to a month to see just how well the Metformin is going to work for you. Do know, that it is VERY rare for a first go to work straight out of the gate! It took them 3 months to get my meds straight! And even then it wasn't perfect (I always had trouble with my morning numbers, altho they were better than yours are doing now!) Eventually tho, they stopped doing their job, and now I'm off the Glipizde and on Insulin and Metformin. It's the nature of the disease. Every so often, things need to be adjusted ... our bodies change, therefore our meds and/or dosages need to change with that.

Good Luck in what ever you/they decide!
__________________
Age: 43
Type 2 - Dx'd 08.16.05
•••
[ A1c ]
6.9 - 01/07
6.0 - 05/07
5.9 - 09/07
6.4 - 3/08
[ Meter ]
UltraSmart/Ultra2/Contour
[ Meds ]
Metformin 1000mg 2x, Novolin N 20u 2x, Novolin R 1:10
Lisinopril 20mg 1x, Lovastatin 40mg 1x, Aspirin 81mg 1x, Albuterol as needed
[ Other Conditions ]
Coccidioidomycosis aka Valley Fever Dx'd 1.17.94
- Asthma
- Chronic Bronchitis
Hypertention
Hyperlipidemia


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  #10 (permalink)  
Old 03-07-2007, 12:35 PM
orpy's Avatar
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Thanks for the supporting answers. It IS frustating. Believe me, this is not the first med I've taken...I've been through Actos, Prandin, I'm on Precose and now Metformin...probably insulin is next...I'm thinking it would be a relief...
__________________
Orpy

A1C changes: 6.8-->6.6-->6.5-->6.1-->6.4-->7.2 --> 6.0-->6.4 (11/2008)

Type 2 or 1.5?

Lantus
Humalog

I have my ups and downs.
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  #11 (permalink)  
Old 03-07-2007, 12:59 PM
mzizgayle's Avatar
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I was on the regular metformin which I took at dinner, but was still experiencing highs and lows no matter what I did, plus the dawn effect was big..I now take 750mg (one pill) of the timed release only at dinner.

My numbers are now staying more consistant, hardly any lows and if there is, it is usually because of my doing, and the dawn effect is practically gone. I am in much better control/consistant with my readings and I don't have any of the stomach distress that I would get with the other.
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  #12 (permalink)  
Old 03-07-2007, 01:44 PM
ladytaz's Avatar
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Quote:
Originally Posted by orpy View Post
Thanks for the supporting answers. It IS frustating. Believe me, this is not the first med I've taken...I've been through Actos, Prandin, I'm on Precose and now Metformin...probably insulin is next...I'm thinking it would be a relief...
You're welcome!

For me insulin was a relief! My numbers kept rising and rising, and I hadn't changed a single thing for them to do so! Now, I've got better control than I've EVER had and I'm SO loving it!! So what, now I have to give myself at least two shots a day (more if I run 160 or more), big deal, it's WELL worth it, to have the better numbers! Makes me more at ease, SO much less stressing about my numbers than I was before, which in turn probably helps with my numbers as well
__________________
Age: 43
Type 2 - Dx'd 08.16.05
•••
[ A1c ]
6.9 - 01/07
6.0 - 05/07
5.9 - 09/07
6.4 - 3/08
[ Meter ]
UltraSmart/Ultra2/Contour
[ Meds ]
Metformin 1000mg 2x, Novolin N 20u 2x, Novolin R 1:10
Lisinopril 20mg 1x, Lovastatin 40mg 1x, Aspirin 81mg 1x, Albuterol as needed
[ Other Conditions ]
Coccidioidomycosis aka Valley Fever Dx'd 1.17.94
- Asthma
- Chronic Bronchitis
Hypertention
Hyperlipidemia


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  #13 (permalink)  
Old 03-07-2007, 01:52 PM
orpy's Avatar
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Posts: 196
[quote=ladytaz;201272]You're welcome!

For me insulin was a relief! QUOTE]

Well, I'm starting to think that it might be for me too! I work really hard...I eat very low carb with barely a treat and run up 26 floors of the building where I work as often as I can. I need a break.

Is there any downside to insulin?
__________________
Orpy

A1C changes: 6.8-->6.6-->6.5-->6.1-->6.4-->7.2 --> 6.0-->6.4 (11/2008)

Type 2 or 1.5?

Lantus
Humalog

I have my ups and downs.
Reply With Quote
  #14 (permalink)  
Old 03-07-2007, 02:16 PM
ladytaz's Avatar
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I am a: Type 2
 
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[quote=orpy;201276]
Quote:
Originally Posted by ladytaz View Post
You're welcome!

For me insulin was a relief! QUOTE]

Well, I'm starting to think that it might be for me too! I work really hard...I eat very low carb with barely a treat and run up 26 floors of the building where I work as often as I can. I need a break.

Is there any downside to insulin?
Yea, I see that you're doing all you possibly can already!! As for downside to insulin ... uhhh .... possible weight gain. I have gained 5 pounds since starting, but then again, I've been eating higher fat foods lately due to financial reasons, costs more to eat 'healthier', yanno! But I'm working right now at taking that back off, and then some! I don't want or need to gain anymore! LOL

I don't know if the weight gain is due to the insulin specifically, or that people in general, tend to eat more stuff, because, well, they can!! Insulin DOES give you that freedom! If you know you're gonna eat a higher carb meal, well, just inject some insulin to cover it! Altho I dont make this a common practice for me!! I still eat my moderately low carb meals (45g or under) as I have been doing since Dx. Have only done that 'cover' deal a couple times.
__________________
Age: 43
Type 2 - Dx'd 08.16.05
•••
[ A1c ]
6.9 - 01/07
6.0 - 05/07
5.9 - 09/07
6.4 - 3/08
[ Meter ]
UltraSmart/Ultra2/Contour
[ Meds ]
Metformin 1000mg 2x, Novolin N 20u 2x, Novolin R 1:10
Lisinopril 20mg 1x, Lovastatin 40mg 1x, Aspirin 81mg 1x, Albuterol as needed
[ Other Conditions ]
Coccidioidomycosis aka Valley Fever Dx'd 1.17.94
- Asthma
- Chronic Bronchitis
Hypertention
Hyperlipidemia


Reply With Quote
  #15 (permalink)  
Old 03-07-2007, 07:03 PM
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Is all insulin by shot? or is there an oral insulin??
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