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Can you go to low on Metformin LinkBack Thread Tools Display Modes
  #16 (permalink)  
Old 05-06-2008, 12:12 PM
fgummett's Avatar
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I am a: Type 2
 
Join Date: Mar 2008
Location: Nova Scotia, Canada
Posts: 2,168
Rx List.com states...

Quote:
Hypoglycemia does not occur in patients receiving GLUCOPHAGE (metformin hydrochloride) or GLUCOPHAGE XR alone under usual circumstances of use, but could occur when caloric intake is deficient, when strenuous exercise is not compensated by caloric supplementation, or during concomitant use with other glucose-lowering agents (such as sulfonylureas and insulin) or ethanol.

Elderly, debilitated, or malnourished patients, and those with adrenal or pituitary insufficiency or alcohol intoxication are particularly susceptible to hypoglycemic effects. Hypoglycemia may be difficult to recognize in the elderly, and in people who are taking beta-adrenergic blocking drug
and...
Quote:
Metformin is an antihyperglycemic agent which improves glucose tolerance in patients with type 2 diabetes, lowering both basal and postprandial plasma glucose. Its pharmacologic mechanisms of action are different from other classes of oral antihyperglycemic agents. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with type 2 diabetes or normal subjects (except in special circumstances) and does not cause hyperinsulinemia. With metformin therapy, insulin secretion remains unchanged while fasting insulin levels and day-long plasma insulin response may actually decrease.
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~ Frank
Metabolic Syndrome Dx'd March 2003. Pumping since April 2004. VSG 20th October 2008
Obesity and Type 2 are strongly associated. Most people assume that Obesity is the cause and Diabetes the effect. It is equally valid to suggest that the underlying metabolic disorder which leads to the Type 2 causes the Obesity.
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  #17 (permalink)  
Old 05-06-2008, 05:28 PM
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I am a: Type 2
 
Join Date: Apr 2008
Location: Louisiana
Posts: 80
I'm glad this question came up. I've been on Metformin for about 2 weeks now. Increased dosage to 1000 mg for about a week now.

I came home from work just now feeling a LOT better than I've felt in a long long time. I feel full of energy. For lunch I had a 1/2 low carb tortilla with ham and cheese and a salad with fresh spinach, 1/2 cucumber, 3 mushrooms, and olive oil / vinegar dressing. I tested my blood sugar with two meters when I got home. Ultra Mini was 98 mg/dL and Relion Ultima was 104.

I didn't have an afternoon snack and I'm ready to go work out. I've been working out really hard almost every day weight lifting and cardio. I saw the 98 mg/dL and that is the first time I've tested since diagnosed being under 100.

I think I'll eat 1/2 nutrition bar ~ 8 carbs before I go work out.

It's good to be aware that one can go low on Metformin but I doubt it would be a hypo that an insulin injecting person would have?
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