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just so you know...b12 LinkBack Thread Tools Display Modes
  #1 (permalink)  
Old 11-28-2008, 04:15 AM
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I am a: Type 2
 
Join Date: Aug 2008
Location: columbus ohio
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just so you know...b12

so. I started metformin in august. last month I started having a tingly and on two occassions numbish toe then I started having muscle twitching. I asked my doctor, he thought it was my statin, took me off. but I still had twitching, thinks the tingling is my numbers coming crashing down. so i go on twitching...for days. so I call his office and he has little to say about it. this is my second doctor, can't seem to find a good one. so I look up muscle twitching on the internet. find b12 deffiency (sp?) so i know met can deplete b12, plus I am eating less than 800 calories a day (whole other issue) but I have not started taking b12. so I go get some liquid, sublingual b12. take it for 3 days, no more twitching...yet. I don't know about tingling, have not had that for a couple weeks.

why do I keep having to figure **** out on my own? I mean b12 depletion can cause permanent nerve damage. Why don't we just start taking it with metformin? too much can't hurt us.

I see an endo on the 8th, sure hope that goes better.
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Old 11-28-2008, 05:10 AM
davef's Avatar
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Location: Dublin, Ireland
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Yannah,

Interesting to hear about B12 deficiency being linked to Metformin use. However as I understand it, our bodies require very little B12 and it is more normal for a vegan, not taking supplements to suffer from a B12 deficiency - don't get me wrong I'm not saying that this is not your problem, I am wondering if the cause of the problem might be your diet as opposed to the Metformin or possible a combination of the two.

I'm no expert (very far from it) on vitamins, but I believe that our bodies normally get B12 from things like eggs, dairy, fish, meat which is why some vegans experience problems.

Your calorie intake at 800 seems very low and I wonder if they food you are eating is providing the B12 or is the metformin impacting on very low levels of B12 that you are getting from food.

Do you mind me asking why your calorie intake is so low?
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Cosmo the Duck: is with Lizzy in SE Michigan.
Ping the Duck: is in Oregon

Metformin 500mg twice daily, Enap 5mg
Diagnosed T2 on 26th Nov'07, with BG of 21mmol/L (378mg/dL) and A1c of 11.6%.
Most recent A1c 08/04/09: 6%
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Old 11-28-2008, 05:29 AM
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dave, I cannot write now going to the airport, will write when I get home. Here is a link.

Diabetes Drugs - Quick Summary
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July 31st 08 10.5
Sept 08 8.3
Oct 21 7.1
Nov21 6.2
March 23 09 5.8

lo carb under 50g a day and excersize
calorie restriction
quinipril- 5 mg a day
metformin ER 500 a day
80 mg varapimil 3 x a day

I LOVE YOU!
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Old 11-28-2008, 08:59 AM
davef's Avatar
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Yannah,

I don't for a moment doubt what you are saying about the link between Metformin and B12 deficiency but I would think it might be worth looking at what your eating too, 800 calories seems very low. Like I said I'm no expert, I do however like to delve a little deeper into things like this and appreciate the heads up on the B12 issue.
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Cosmo the Duck: is with Lizzy in SE Michigan.
Ping the Duck: is in Oregon

Metformin 500mg twice daily, Enap 5mg
Diagnosed T2 on 26th Nov'07, with BG of 21mmol/L (378mg/dL) and A1c of 11.6%.
Most recent A1c 08/04/09: 6%
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Old 11-28-2008, 03:39 PM
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Hi Dave the muscle twitching came back on the plane.

My calorie intake is for ****. I just can't want to eat since DX.

I keep loosing wieght at the speed of light. It probably has alot to do with my menstrual cycle being all screwed up and the diarrhea. who know what else. but i have no appetite at all.
__________________
July 31st 08 10.5
Sept 08 8.3
Oct 21 7.1
Nov21 6.2
March 23 09 5.8

lo carb under 50g a day and excersize
calorie restriction
quinipril- 5 mg a day
metformin ER 500 a day
80 mg varapimil 3 x a day

I LOVE YOU!
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  #6 (permalink)  
Old 11-28-2008, 03:44 PM
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I found the the Met really cut my appetite and I was only eating at meal times and not becuase I was hungry
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Cosmo the Duck: is with Lizzy in SE Michigan.
Ping the Duck: is in Oregon

Metformin 500mg twice daily, Enap 5mg
Diagnosed T2 on 26th Nov'07, with BG of 21mmol/L (378mg/dL) and A1c of 11.6%.
Most recent A1c 08/04/09: 6%
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Old 11-28-2008, 05:17 PM
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I've read that metformin can deplete B12...so I take a good multivitamin and a B12 supplement. So far, so good.
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Metformin 500 mg twice daily
HCTZ 12.5 mg every other day for BP
Enalapril 20 mg 1 daily (ace-inhibitor)
Lower carb dieter (approx. 75 total carbs/day, more on weekends), taking chromium, multivitamin and fish oil tablets


Initial A1C 8/06: 9.6
11/06: 6.2.
03/07: 5.3
06/07: 5.4
10/07: 5.3
05/08: 6.2 (after dealing with shingles & bronchiti)
2/09: 5.5
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Old 11-28-2008, 06:07 PM
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I wish the metformin would cut my appetite, I am always sooooooooo hungry.

The diarrhea goes away or well subsides anyways, I have been taking metformin since june and diarrhea doesn't affect me that much now, for which my butt thanks me
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April 09 A1c 6.2%
Dec 08 A1c 6.2%
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June 08 A1c 8.5%

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Glypizide 10mg occassionaly when I want to eat lots of carbs
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Old 11-29-2008, 02:58 AM
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Quote:
Originally Posted by PrettynPurple View Post
I wish the metformin would cut my appetite, I am always sooooooooo hungry.

The diarrhea goes away or well subsides anyways, I have been taking metformin since june and diarrhea doesn't affect me that much now, for which my butt thanks me
I am the same way... seems I can't stop eating... it ok when I have things like brocilli or celery in the house but when I'm out I go for the bad stuff ... today I been good and the last three tests were 82, 102 and 91
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Humulin U-500 Pumping Pink Ping
Metformin 850mg 3x a day
Cpap 18 Cm H2o with Ultra Mirage Full Face Mask
Aspirin 162 mg a day
Zetia 10mg a day
Tricor 145mg a day
Benazepril 20mg a day
Dyazide 27.5-25mg a day
Metoprolol 50mg a day
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