[jrdiabetic]

I have been taking Glipizide with metformin for the past 2 days, I have a severe diahria since I started Glipizide. Is it common? or should I stop taking Glipizide?

Thanks.

[jtausch]

did you start both or just the glizide? I know metformin can cause diarrhea but I am not sure about the other

[Granny Shanny]

So you were taking metformin before starting the glipizide & suffered no side effects?

I've never used glipizide, but metformin definitely caused diarrhea for me the first few days.

[Dan Gato]

Lower your Metformin dosage.
It's OK to cut in half, I do it.

In general Glip doesn't have those side effects.
Also, don't drink milk before your meds & reduce splenda
or other sweeteners, it isn't the Glipizide, look at other factors.

Good luck.

[cyberus]

BTW

Its ok to split metformin as long as its not the XR/ER/TR version which are NOT ok to split in half

[jrdiabetic]

Thanks to everyone for your response. I guess it could be because of milk (Morning cereal) before my medication.

Thanks.

Originally Posted by Dan Gato

Lower your Metformin dosage.
It's OK to cut in half, I do it.

In general Glip doesn't have those side effects.
Also, don't drink milk before your meds & reduce splenda
or other sweeteners, it isn't the Glipizide, look at other factors.

Good luck.

[Gozelle]

I had the same kind of problem for months on Metformin and then all of a sudden it is not a problem. Guess my body just needed to adjust.

[georgepds]

So I read that one side effect of metformin could be Alzeheimmers

Does Glucophage Make Alzheimer's Worse?. In the Pipeline:

" In cell culture, metformin seems to increase the amount of beta-amyloid generated by neurons. If you buy into the beta-amyloid hypothesis of Alzheimer’s, that’s very bad news indeed"

Wait a sec.. what were we talking about agian..opps wrong end.. must be the AD kicking in