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Kimberleyjc

Medication besides Insulin

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Hi all-

 

i'm wondering what medication people are on besides insulin injections/pump. I've heard of some type 1s being put on metformin?

 

Also wondering about complications medications- do you take anything for neuropathy, kidneys, heart disease or anything else?

 

Thanks!

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Hi all-

 

i'm wondering what medication people are on besides insulin injections/pump. I've heard of some type 1s being put on metformin?

 

Also wondering about complications medications- do you take anything for neuropathy, kidneys, heart disease or anything else?

 

Thanks!

 

A few go on metphormin, but most endo's will not want to do this.

 

Most of us are on ACE inhibitors for kidney protection. Many are on statins for heart disease. I can't help with the neuropathy stuff, yet.

 

A few also go on something called Symlin. Google "scheiner symlin" It replaces amylin which our dead beta cells don't produce. It's a synthetic hormone to suppress glucagon release and therefore gluconeogenesis. I don't know too much about it as it's not available in Canada. My understanding is it can be very inconsistant. Risk of hypoing escalates. I'm betting they want people who really understand their own behavior before letting them on it.

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I only use insulin via a pump for my diabetes.

No statins or ace inhibs..... No complications either.

45 years with type 1 diabetes.

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I'm a type 1 pumper (Novolog) who has been taking Metformin (500-mg) for over 6 years. My Endo & I feel it helps to keep my weight steady, and I truly feel that it is.

 

I also take 10mg Crestor for cholesterol.

 

Karen

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Take an ARB for kidneys as a protective measure (ACE inhibitors made me cough too much and since I have asthma that's a concern). That medication will change next month since it's not pregnancy approved. I took symlin at one point but the previous poster was correct, you need very good control to be on it and prevent hypos, it helped me lose a lot of weight though :) Take meds also for migraines and asthma and OTC stuff to help with digestion since I have gastroparesis. If I'm going to have a meal that's super tough to digest I have reglan but I can't use it often and in 2 months at all during TTC time.

 

Fawn

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I use Humalog in a pump. I also take Levoxyl for my thyroid and Advair for asthma. Insulin is the only drug I've ever used to treat my diabetes. No complications so no meds for anything like that.

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A few go on metphormin, but most endo's will not want to do this.

 

 

 

Is there a reason that endos don't want people on metformin?

 

Gwennie

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It is so CHEAP, too ...

 

Still confused. They don't want people to be on it because it is cheap?? Any other reasons?

 

Gwennie

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I think you may have misunderstood Linda's comment - I think she meant that it's surprising that more T1's don't take it since it's so cheap.

 

Some doctors do prescribe it for T1's with insulin resistance and to deal with glucose release by the liver. Many T1's are insulin sensitive and don't need help in that area. And some Endos just don't consider when it might be useful for T1's.

 

Jen

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There are times I would love to shut my stupid liver off!! I have no problems with resistance other than the periods where, for no known reason, I end up needing 50% more insulin for a few days and at times, weeks. Then things suddenly return to normal. For the most part it's not a problem. I do hate liver dumps, though, but I'm not really wanting to take a pill with unpleasant side effects to see if it makes enough of a difference.

 

Is there an increased hypo risk for Type 1s taking metformin? When I was on MDI and would have severe lows as I slept my liver was the only thing that saved me as I was unable to move and get something to treat the low. With a pump I'm not nearly as worried about overnight lows but I still wouldn't want to take a chance.

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I was diagnosed at age 18 (almost 4 yrs ago) with type 1 diabetes and was immediately put on insulin. Humalog insulin is the only med that I've ever used to treat my diabetes. I used insulin via injection for 2 yrs and finally got my Animas Ping pump about 2 yrs ago. I absolutely love it and I really believe it has saved my life (It's so much easier and convenient). I also take Synthroid (Levothyroxin) for my thyroid.

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I take an ACE inhibitor and a statin also. Just started meds for neuropathy. The doctor suggested adding metformin, but mystomach can't tolerate it.

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Is there an increased hypo risk for Type 1s taking metformin? When I was on MDI and would have severe lows as I slept my liver was the only thing that saved me as I was unable to move and get something to treat the low. With a pump I'm not nearly as worried about overnight lows but I still wouldn't want to take a chance.

 

Liz, I can only relate my experience, with either 500 or 1000mg of met ER (the long lasting stuff). I have found that as well as decreasing a tendency to biologically spike from ?? influences such as temperature, stress, etc, and decreasing slightly the spike from carbs, I tend to have less severe hypos as well.

 

This is my thought why, though I don't know for sure. Met doesn't seem to completely stop you from storing glucagon/glucose, it mainly seems to throttle the extremes back. In my case, a typical scenario is that I have a lot of basal spiking/liver release through the day, and come the evening I switch to having a tendency for nasty hypos, even given pulling back on basal with the pump.

 

My conjecture is that I have a liver that likes to switch on when I get moving in the morning, and basically exhaust itself on a daily basis. What happened when I added the met, was that I didn't get such an upward push during the day, and I didn't get the downward severity with hypos in the evening (and recovery was easier, so I assume a little more help metabolically).

 

I don't think my spike through the day is typical, but that is what I found for myself and might provide some basis for comparison. It seemed to increase stability, not decrease ability to recover from a hypo.

 

I do find I can't stomach much (hence I'm back on 500mg, at this rate it has no GI side effects) and the effect is not very strong - but for me worth the tradeoff of cost, taking the pills, minor side effects etc. I've had a query raise in my head lately, as I have had a tender liver area and my enzymes were slightly raised leading my endo to mutter about fatty liver, which has never happened before. (I need to investigate those test results further with my GP, who ironically is the one I can talk through issues in detail). It's on the possible culprit table for me right now, (for what, not quite sure) so I'm not currently fully endorsing it myself!

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I am on the laundry list of cooly colored pills for the stated reasons:

 

Glimepiride 1mg x 2 daily to control sugar (replaced Metformin)

Pioglitazone 30 mg (morning) 15mg (evening) to stimulate insulin/cell absorption; also referred to as Actos

Lisinopril 5mg x 1 daily for kidney wear and tear

Clopidogrel 75mg x 1 daily for heart disease prevention (I'm allergic to Aspirin)

B12 1000mg x 1 daily for neuropathy

Fish Oil tablet x 1 daily for beta stimulation

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A few go on metphormin, but most endo's will not want to do this.

 

Most of us are on ACE inhibitors for kidney protection. Many are on statins for heart disease. I can't help with the neuropathy stuff, yet.

 

A few also go on something called Symlin. Google "scheiner symlin" It replaces amylin which our dead beta cells don't produce. It's a synthetic hormone to suppress glucagon release and therefore gluconeogenesis. I don't know too much about it as it's not available in Canada. My understanding is it can be very inconsistant. Risk of hypoing escalates. I'm betting they want people who really understand their own behavior before letting them on it.

Hi X-menace, I have not heard of ACE inhibitors, is that more for adults with type1 who have diabetes for years?

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Hi X-menace, I have not heard of ACE inhibitors, is that more for adults with type1 who have diabetes for years?

 

Ace Inhibitors are a common blood pressure medication. The most common one that I know of is Lisinopril. The one side effect is the nagging cough that seems to accompany this medication. And it can be started at anytime if a person has higher than normal blood pressure. The cough can be more than annoying as it disrupts sleep and everything else. If you are put on it and have the cough ask the doctor to use something else such as an ARB

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I take an ACE inhibitor to protect the kidneys from the high bgs. I also take a statin to protect against heart disease.

My blood pressure is actually normal, and my cholesterol is good, but for diabetics, the doctors want it beyond good.

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