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William V

low-dose aspirin has no CV benefit for Type 2

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Study of ~2500 Japanese type 2 diabetes people shows low-dose aspirin therapy did not reduce cardiovascular events in patients with type 2 diabetes in primary prevention setting for 10-year follow-up. Mean patient age was 65 years at baseline, and 55% of patients were males. Mean duration of diabetes was 7.1 years. They found no significant between group difference for the primary end point of CV events, including sudden death, coronary artery disease, stroke, and peripheral artery disease. Also no significant differences in hemorrhagic stroke. Gastrointestinal bleeding occurred more often in the aspirin group  2% than the no-aspirin group 0.9%.

References

Saito Y, Okada S, Ogawa H, et al. The long-term therapy with low-dose aspirin did not reduce cardiovascular events in patients with type 2 diabetes in primary prevention: 10-year follow-up of a randomized controlled trial. Circulation 2016; DOI:CIRCULATIONAHA/2016/025760R2

 

http://circ.ahajournals.org/content/134/Suppl_1/A13428

meyery2k, OldTech, adiantum and 1 other like this

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Years ago when I went to ER with chest pains the doctor immediately gave me 2 aspirin then did an ECG etc

 

The pains were a side effect of BP meds but I learned a good trick from that experience.

If I get a chest pain, I take 2 Aspirin & all is well once more

TX_Clint and meyery2k like this

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I have to wonder how much of the aspirin/statin craze is due to patients demanding their doctors demand action be taken even if there's nothing wrong. nothing wrong.

 

Art

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My cardiologist had me on low dose aspirin for a few years. But after I started starting krill oil, I reached the conclusion that the two things combined might be thinning my blood too much, so I dropped the aspirin. Now I even back off on the krill oil when it appears my blood is getting a little too thin. With fingertip tests an average of six times a day plus bruising from the insulin injections, I feel I can get a pretty good idea of when the blood is thinner than normal. 

Orlando and meyery2k like this

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Years ago when I went to ER with chest pains the doctor immediately gave me 2 aspirin then did an ECG etc

 

The pains were a side effect of BP meds but I learned a good trick from that experience.

If I get a chest pain, I take 2 Aspirin & all is well once more

 

Just make sure they aren't enteric coated which helps prevent upset stomach.  The idea of aspirin for chest pain or suspected heart attack is to chew uncoated 325mg. to get it in the blood stream fast.  I found USA made non coated aspirin in the $ store and keep some on hand, otherwise I would buy it anywhere I could find it.

adiantum likes this

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Well aspirin is an anti-inflammatory and diabetes (all kinds) cause inflammation. I suppose that is a benefit of sorts. I don't take aspirin because I find I bruise afterwards. But, then, I don't take anything else either. I firmly believe in "Don't fix it if it ain't broke".

TX_Clint, adiantum and Orlando like this

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From time to time I tell my cardiolog that I have stopped taking a certain pill. Some time ago I tested him with "stopped the statins", he didnt blink. Tested him months re aspirin and he almost jumped out of his chair, advising in no uncertain terms "never stop taking the baby aspirin". 

adiantum likes this

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