Jump to content
Diabetes forums
  • Welcome To Diabetes Forums!

    Registration is fast, simple and absolutely free so please, join our community today to contribute and support the site.

Archived

This topic is now archived and is closed to further replies.

zookeeper671

"Lyrica Relieves Diabetes Pain"

Recommended Posts

zookeeper671

Lyrica Relieves Diabetes Pain

 

NEW YORK (Reuters Health) - A new drug, Lyrica (pregabalin) is a well-tolerated, effective treatment for pain in the extremities often experienced by people with diabetes, according to a recent report. In addition to reducing the pain, the drug seems to improve sleep.

 

The findings, which appear in the medical journal Neurology, are based on a study sponsored by Pfizer, which markets Lyrica. Just last week, the FDA (news - web sites) approved the drug specifically for painful diabetic neuropathy.

 

The study involved 338 patients with diabetes-related pain who were randomly given Lyrica, at one of three doses, or inactive "placebo" for five weeks.

 

The intermediate and highest doses of Lyrica, but not the lowest dose, were better than placebo at improving pain, Dr. Harold Lesser, from the University of Rochester School of Medicine & Dentistry in New York, and colleagues note. These doses were also tied to significant improvements in sleep and quality of life.

 

People who were given Lyrica were also more likely to have a treatment response, meaning that they had a 50 percent or greater improvement in their pain. The two higher doses of Lyrica had responder rates of around 47 percent, whereas the rate with placebo was just 18 percent.

 

The improvements in pain and sleep were noted within 1 week of treatment with Lyrica and continued throughout the study, the investigators point out.

 

Treatment with Lyrica was well tolerated and side effects were generally mild, most commonly dizziness and sleepiness, the report indicates.

 

The results suggest that Lyrica has the potential to become a first-line treatment for diabetes pain, Lesser's team notes.

 

SOURCE: Neurology, December 15, 2004.

Share this post


Link to post
Share on other sites

×

Important Information

By using this site, you agree to our Terms of Use.